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Sclerotherapy, New Discoveries on Cell-Touching and Ultrasound to Cure Strokes

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Sclerotherapy

By now we all know that sclerotherapy means the injection of a solution to eliminate spider veins. I would like to spend a little time with you and explain the beginnings and current therapies available.

In 1831 Dr. Prevaz, a Portuguese military Surgeon, invented the syringe as we know it today. Ten years later a Dutch Physician by the name of Dr. Rynd, invents the metallic needle. Within two years they were injecting 200 proof alcohol with disastrous results. There was massive inflammation and blood clots. The early users used arsenic and mercury, various sugars, iodine, iron mixtures and all sorts of toxic solutions that they thought would eliminate varicose veins. In the early 1920s a French Phlebologist, Dr Sicard, began using a solution of Salicylate (a form of aspirin). They not only hit upon a solution that was safe, albeit painful, but it also had an unexpected side effect – it made the pain of their arthritis dissipate. Mr. Bayer a German Chemist picked up on that and aspirin was born. In the 1930s and 1940s almost all of the solutions that we use today were invented. There has not been a new sclerosing solution in over 50 years.

So what is available today? Everybody would like lasers to take care of their spider veins, but the reason no laser today works successfully on spider veins is that spider veins are not always the main cause. The feeding ‘reticular’ veins, those larger and deeper blue veins, which are also called ‘feeder’ veins are the real cause and unless those are sclerosed (injected first) the spider veins will quickly return which is why today sclerotherapy is still the gold standard. Think of it like this, you have a sprinkler system; under the ground are the pipes that feed water to the sprinklers above ground. If one of the sprinklers stops working and you only fix the sprinkler without checking the underground pipes first, you might only be masking the root of the problem. Same with spider veins or varicose veins, if you have superficial veins that are less than esthetically pleasing, then it is best to check the “piping” before fixing the leak, otherwise you could be masking a much larger problem.

Lasers are however, the gold standard for facial veins. The veins above the heart are trying to collapse by gravity while the veins below the heart are trying to stay open. We never inject the facial veins because there are so many A-V malformations (arterial-venous malformation) in that area and should solution get into one of them, the patient is at a much higher risk of having a severe scarring ulcer on the face.

Now is the time to start having your veins treated so that by the time Spring comes, (and it feels like it never will this year) you’ll be ready. So in these times of Obamanomics we will offer a 10% discount through the month of March. Think of it as a tax incentive to stimulate the looks of your legs!

NEW DISCOVERIES ON CELL-TOUCHING

There are more cells in your body than there are stars in the universe, but how do they know where to go and what to do without some sort of direction. Up until now most have said that each cell responds to its surroundings by chemical messengers or by cytokines(cells that secrete a protein or messenger next to the cell it is influencing). Let’s face it they can’t see, hear, feel or smell . Or can they? The cytokine theory says that they can “smell” a chemical messenger but what about tissue that has no or little blood supply such as cartilage. How can a cytokine work in such an environment?

The latest findings are that cells “feel” their way to perform their specific functions. If one tries to grow bone stem cells on a soft matrix the ensuing bone is soft and weak, but when the matrix is stiffened the ensuing bone cells develop into strong bony tissue. If we take stem cells and expose them to flowing fluid they turn into blood vessels. When stem cells are exposed to rhythmic forces they turn into heart cells or cartilage cells, in other words if you mimic the environment to which a cells is ultimately destined to be you can influence the final specialty of that cells. In an experiment at the University of Pennsylvania they grew stem cells in a Petri dish and exposed the outer regions to stresses and the inner core to virtually no stress. The outer portions of the dish turned into bone cells while the inner sections turned into fat cells. So it appear that cell growth may well be influenced by cytokines but also and to a great extent by the “touch and pressure” of the environment within which the cells finds itself.

Tumors, lumps and bumps are usually found by feeling and represent stiffened tissue that we say needs biopsy or further investigation. Paul Janmey at the University of Pennsylvania found that cell division of breast cells stops when fully grown on a soft gel and they remained in a quiescent state but when made rigid by any method they started growing again increasing the risk of cancer. In a similar experiment of the U. of C San Francisco they took breast tissue cells and grew them in a soft media which made them less likely to form into malignant cells. This may explain why women with very dense fibrous breast tissue are more likely to develop breast cancer than those who do not have dense tissue and why there is a higher incidence of tumors arising from the scar tissue of breast implants.

Editors Note; All of this makes perfect sense. Back in the 1980’s we found that if women took 1000 IU’s of Natural Vitamin E for 6 months there was a drastic reduction in the mammographic appearance of their fibro-cystic disease. Their incidence of breast discomfort and cancer were both reduced. In some studies they used synthetic Vitamin E and had minimal results, but since Natural Vitamin E is 7 times more potent than its synthetic counter part those studies showed dramatic decreases in breast cancer. In countries such as Japan where the majority of their protein is either from soy or fish and where both fibrocystic disease and breast cancer are at their lowest one should also consider the effects of our diets on disease.

ULTRASOUND TO CURE STROKES

The University of San Diego is using an ultrasonic devise that generates signals from 1000 ultrasound transducers focusing on a blood clot in the brain to break it up. Currently the only two ways to dissolve blood clots are to inject a solution of TPA within three hours of the stroke or surgically attempt to remove it. With this non invasive devise ultrasound is generated through the skull and focused on the clot, and with sound waves breaks it up. It’s still experimental, but looks like it will save a lot of lives and recuperation. Currently, strokes are the largest cause of long term disabilities in the U.S. and the number one and two causes are hypertension (high blood pressure) and high cholesterol.

Lipocavitron and Ultrasonic-Lipodissolve

As many of you know we have been developing the Lipodissolve for quite some time. We have reduced the pain to almost nothing and the recovery with the cold laser has reduced the amount of swelling time to less than a week. While recently reviewing the literature I came across an article written by a French Physician, Dr. Thierry Marechal, who was using his Lipocavitron machine with Lipodissolve. The more I read the more I became upset with myself for not having thought of this sooner.

It appears that when he used his Lipocavitron machine alone he was getting an average loss of 5.5 cm (2 ¼ inches) and when he used the Lipodissolve alone he was having an average loss of 8 cm (3 inches), but when he combined the two treatments, his average loss was an astounding 13.5 cm (5 ¼ inches)! That is remarkable for a non invasive procedure. I personally think that is very close to traditional Liposuction. We have already begun the using Lipocavitron in conjunction with Lipodisolve on our patients and the results are pretty amazing.

What is Lipocavitron? It is a 29 KHz ultrasound devise that puts sound waves very superficially through your skin. It is totally painless and has no adverse side effects whatsoever. I have the only Lipocavitron in the U.S. The FDA explained it to me this way; one machine is allowed into the U.S., but two is “distribution”. The Swiss company that makes it will have to go through all of the FDA approval process in order to sell a second machine. Most small European companies cannot afford that lengthy and expensive process. There are literally thousands of these machines in work all over Europe for the last 25 years, but not until recently did anyone think to combine the two technologies.

So since we now have this technology we are offering this to our patients – if you want to lose 5 ¼ inches off of your abdomen this is probably the least expensive and non invasive tool ever.

And here is a BONUS/contest …I like the name “Ultrasonic Lipodissolve”, however it’s not that catchy. Therefore, I challenge all of you to try to come up with a better name for the treatment. Should I select your creative idea, I will give you one full session – free of charge.

(Some restrictions apply.)

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5 Responses to “Sclerotherapy, New Discoveries on Cell-Touching and Ultrasound to Cure Strokes”

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